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Mass Obliteration
Obliterate 50 crafted items in the Obliterum Forge.
Mass Obliteration requires you to Obliterate 50 crafted items at the Obliterum Forge, and the fastest way is to purchase cheap Legion Alchemy potions from the Auction House and obliterate them one by one.
Buy Potions from AH
Purchase 50 
Ancient Healing Potion or 
Ancient Mana Potion from the Auction House — both are craftable Legion Alchemy potions that count toward the achievement. If those are unavailable or expensive, 
Draught of Raw Magic also qualifies but tends to cost more on most realms.
Obliterate at the Forge
Take your 50 purchased potions to the Obliterum Forge in Dalaran (Legion) and obliterate them one at a time. Each potion obliterated counts as one toward the 50 required, and each obliteration yields 1–2 
Obliterum Ash as a bonus.
Tips
With enough
Obliterum Ash collected, you can craft 
Obliterum to upgrade Legion crafted gear — see the video guides for a full walkthrough of the forge process.